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Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation

Overexpression of enhancer of zeste homologue 2 (EZH2) occurs in various malignancies and is associated with a poor prognosis, especially because of increased cancer cell proliferation. In this study we found an inverse correlation between EZH2 and RUNX3 gene expression in five cancer cell lines, i....

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Detalles Bibliográficos
Autores principales:	Fujii, Satoshi, Ito, Kosei, Ito, Yoshiaki, Ochiai, Atsushi
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Transcription, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427338/ https://www.ncbi.nlm.nih.gov/pubmed/18430739 http://dx.doi.org/10.1074/jbc.M800224200

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