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A Common β-Sheet Architecture Underlies in Vitro and in Vivo β(2)-Microglobulin Amyloid Fibrils

Misfolding and aggregation of normally soluble proteins into amyloid fibrils and their deposition and accumulation underlies a variety of clinically significant diseases. Fibrillar aggregates with amyloid-like properties can also be generated in vitro from pure proteins and peptides, including those...

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Detalles Bibliográficos
Autores principales:	Jahn, Thomas R., Tennent, Glenys A., Radford, Sheena E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427364/ https://www.ncbi.nlm.nih.gov/pubmed/18424782 http://dx.doi.org/10.1074/jbc.M710351200

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