A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction

We used nuclear magnetic resonance data to determine ensembles of conformations representing the structure and dynamics of calmodulin (CaM) in the calcium-bound state (Ca(2+)-CaM) and in the state bound to myosin light chain kinase (CaM-MLCK). These ensembles reveal that the Ca(2+)-CaM state include...

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Detalles Bibliográficos
Autores principales: Gsponer, Jörg, Christodoulou, John, Cavalli, Andrea, Bui, Jennifer M., Richter, Barbara, Dobson, Christopher M., Vendruscolo, Michele
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428103/
https://www.ncbi.nlm.nih.gov/pubmed/18462678
http://dx.doi.org/10.1016/j.str.2008.02.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428103/
https://www.ncbi.nlm.nih.gov/pubmed/18462678
http://dx.doi.org/10.1016/j.str.2008.02.017

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