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A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction
We used nuclear magnetic resonance data to determine ensembles of conformations representing the structure and dynamics of calmodulin (CaM) in the calcium-bound state (Ca(2+)-CaM) and in the state bound to myosin light chain kinase (CaM-MLCK). These ensembles reveal that the Ca(2+)-CaM state include...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2428103/ https://www.ncbi.nlm.nih.gov/pubmed/18462678 http://dx.doi.org/10.1016/j.str.2008.02.017 |