Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis

BACKGROUND: The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas in past decades, a handful of tumor suppressors have been slowly identified using te...

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Detalles Bibliográficos
Autores principales: Chan, Timothy A, Glockner, Sabine, Yi, Joo Mi, Chen, Wei, Van Neste, Leander, Cope, Leslie, Herman, James G, Velculescu, Victor, Schuebel, Kornel E, Ahuja, Nita, Baylin, Stephen B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429944/
https://www.ncbi.nlm.nih.gov/pubmed/18507500
http://dx.doi.org/10.1371/journal.pmed.0050114

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