Prolonged Classical NF-κB Activation Prevents Autophagy upon E. coli Stimulation In Vitro: A Potential Resolving Mechanism of Inflammation

Activation of NF-κB is known to prevent apoptosis but may also act as proapoptotic factor in order to eliminate inflammatory cells. Here, we show that classical NF-κB activation in RAW 264.7 and bone marrow-derived macrophages upon short E. coli coculture is necessary to promote cell death at late t...

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Detalles Bibliográficos
Autores principales: Schlottmann, Silke, Buback, Franziska, Stahl, Bettina, Meierhenrich, Rainer, Walter, Paul, Georgieff, Michael, Senftleben, Uwe
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430012/
https://www.ncbi.nlm.nih.gov/pubmed/18566685
http://dx.doi.org/10.1155/2008/725854

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