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Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis

BACKGROUND: The major histocompatibility complex (MHC) is essential for human immunity and is highly associated with common diseases, including cancer. While the genetics of the MHC has been studied intensively for many decades, very little is known about the epigenetics of this most polymorphic and...

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Detalles Bibliográficos
Autores principales: Tomazou, Eleni M, Rakyan, Vardhman K, Lefebvre, Gregory, Andrews, Robert, Ellis, Peter, Jackson, David K, Langford, Cordelia, Francis, Matthew D, Bäckdahl, Liselotte, Miretti, Marcos, Coggill, Penny, Ottaviani, Diego, Sheer, Denise, Murrell, Adele, Beck, Stephan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430202/
https://www.ncbi.nlm.nih.gov/pubmed/18513384
http://dx.doi.org/10.1186/1755-8794-1-19