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Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice

BACKGROUND: The rate at which a stretch of DNA mutates is determined by the cellular systems for DNA replication and repair, and by the nucleotide sequence of the stretch itself. One sequence feature with a particularly strong influence on the mutation rate are nucleotide repeats. Some microbial pat...

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Detalles Bibliográficos
Autores principales: Wanner, Roger M, Güthlein, Carolin, Springer, Burkhard, Böttger, Erik C, Ackermann, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430213/
https://www.ncbi.nlm.nih.gov/pubmed/18507851
http://dx.doi.org/10.1186/1471-2164-9-249