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Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice
BACKGROUND: The rate at which a stretch of DNA mutates is determined by the cellular systems for DNA replication and repair, and by the nucleotide sequence of the stretch itself. One sequence feature with a particularly strong influence on the mutation rate are nucleotide repeats. Some microbial pat...
Autores principales: | Wanner, Roger M, Güthlein, Carolin, Springer, Burkhard, Böttger, Erik C, Ackermann, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430213/ https://www.ncbi.nlm.nih.gov/pubmed/18507851 http://dx.doi.org/10.1186/1471-2164-9-249 |
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