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Cytostatic drug treatment causes seeding of gene promoter methylation
Epigenetic changes in multiple genes are emerging as an important mechanism for tumour cells to acquire resistance to chemotherapy. In the present work, we test the hypothesis that epigenetic organisation in cancer cells can be affected by cytostatic drugs. Colorectal cancer cells were cultured for...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430383/ https://www.ncbi.nlm.nih.gov/pubmed/17236756 http://dx.doi.org/10.1016/j.ejca.2006.12.003 |