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Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

BACKGROUND: Aβ deposits in the brains of patients with Alzheimer's disease (AD) are closely associated with innate immune responses such as activated microglia and increased cytokines. Accumulating evidence supports the hypothesis that innate immune/inflammatory responses play a pivotal role in...

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Detalles Bibliográficos
Autores principales:	Jin, Jing-Ji, Kim, Hong-Duck, Maxwell, J Adam, Li, Ling, Fukuchi, Ken-ichiro
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430555/ https://www.ncbi.nlm.nih.gov/pubmed/18510752 http://dx.doi.org/10.1186/1742-2094-5-23

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