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Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae

The ribosomal DNA (rDNA) genes of Saccharomyces cerevisiae are located in a tandem array of about 150 repeats. Using a diploid with markers flanking and within the rDNA array, we showed that low levels of DNA polymerase alpha elevate recombination between both homologues and sister chromatids, about...

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Detalles Bibliográficos
Autores principales:	Casper, Anne M., Mieczkowski, Piotr A., Gawel, Malgorzata, Petes, Thomas D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430618/ https://www.ncbi.nlm.nih.gov/pubmed/18584028 http://dx.doi.org/10.1371/journal.pgen.1000105

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