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Prediction of enzyme function by combining sequence similarity and protein interactions
BACKGROUND: A number of studies have used protein interaction data alone for protein function prediction. Here, we introduce a computational approach for annotation of enzymes, based on the observation that similar protein sequences are more likely to perform the same function if they share similar...
Autores principales: | Espadaler, Jordi, Eswar, Narayanan, Querol, Enrique, Avilés, Francesc X, Sali, Andrej, Marti-Renom, Marc A, Oliva, Baldomero |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430716/ https://www.ncbi.nlm.nih.gov/pubmed/18505562 http://dx.doi.org/10.1186/1471-2105-9-249 |
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