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Man versus Machine versus Ribozyme

A microfluidic device has been constructed to carry out the automated, continuous evolution of ribozymes. A comparison with manual efforts reveals that both are capable of far flung forays into sequence space.

Detalles Bibliográficos
Autor principal: Ellington, Andrew D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430915/
https://www.ncbi.nlm.nih.gov/pubmed/18507505
http://dx.doi.org/10.1371/journal.pbio.0060132
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author Ellington, Andrew D
author_facet Ellington, Andrew D
author_sort Ellington, Andrew D
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description A microfluidic device has been constructed to carry out the automated, continuous evolution of ribozymes. A comparison with manual efforts reveals that both are capable of far flung forays into sequence space.
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spelling pubmed-24309152008-06-19 Man versus Machine versus Ribozyme Ellington, Andrew D PLoS Biol Primer A microfluidic device has been constructed to carry out the automated, continuous evolution of ribozymes. A comparison with manual efforts reveals that both are capable of far flung forays into sequence space. Public Library of Science 2008-05 2008-05-27 /pmc/articles/PMC2430915/ /pubmed/18507505 http://dx.doi.org/10.1371/journal.pbio.0060132 Text en © 2008 Andrew D. Ellington. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Primer
Ellington, Andrew D
Man versus Machine versus Ribozyme
title Man versus Machine versus Ribozyme
title_full Man versus Machine versus Ribozyme
title_fullStr Man versus Machine versus Ribozyme
title_full_unstemmed Man versus Machine versus Ribozyme
title_short Man versus Machine versus Ribozyme
title_sort man versus machine versus ribozyme
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430915/
https://www.ncbi.nlm.nih.gov/pubmed/18507505
http://dx.doi.org/10.1371/journal.pbio.0060132
work_keys_str_mv AT ellingtonandrewd manversusmachineversusribozyme