Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

BACKGROUND: Recent evidence suggests that oxytocin (OT), secreted in the superficial spinal cord dorsal horn by descending axons of paraventricular hypothalamic nucleus (PVN) neurons, produces antinociception and analgesia. The spinal mechanism of OT is, however, still unclear and requires further i...

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Detalles Bibliográficos
Autores principales: Breton, Jean-Didier, Veinante, Pierre, Uhl-Bronner, Sandra, Vergnano, Angela Maria, Freund-Mercier, Marie José, Schlichter, Rémy, Poisbeau, Pierrick
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430948/
https://www.ncbi.nlm.nih.gov/pubmed/18510735
http://dx.doi.org/10.1186/1744-8069-4-19

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