Immunostimulatory effects of three classes of CpG oligodeoxynucleotides on PBMC from HCV chronic carriers

BACKGROUND: Chronic hepatitis C virus (HCV) infection results from weak or absent T cell responses. Pegylated-interferon-alpha (IFN-α) and ribavirin, the standard of care for chronic HCV, have numerous immune effects but are not potent T cell activators. A potent immune activator such as TLR9 agonis...

Descripción completa

Detalles Bibliográficos
Autores principales: Cooper, Curtis L, Ahluwalia, Navneet K, Efler, Susan M, Vollmer, Jörg, Krieg, Arthur M, Davis, Heather L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430961/
https://www.ncbi.nlm.nih.gov/pubmed/18541039
http://dx.doi.org/10.1186/1476-8518-6-3

Ejemplares similares

Ejemplares similares