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Global Mapping of DNA Methylation in Mouse Promoters Reveals Epigenetic Reprogramming of Pluripotency Genes

DNA methylation patterns are reprogrammed in primordial germ cells and in preimplantation embryos by demethylation and subsequent de novo methylation. It has been suggested that epigenetic reprogramming may be necessary for the embryonic genome to return to a pluripotent state. We have carried out a...

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Detalles Bibliográficos
Autores principales:	Farthing, Cassandra R., Ficz, Gabriella, Ng, Ray Kit, Chan, Chun-Fung, Andrews, Simon, Dean, Wendy, Hemberger, Myriam, Reik, Wolf
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432031/ https://www.ncbi.nlm.nih.gov/pubmed/18584034 http://dx.doi.org/10.1371/journal.pgen.1000116

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