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Plasma PCSK9 levels are significantly modified by statins and fibrates in humans
BACKGROUND: Proprotein convertase subtilisin kexin-like 9 (PCSK9) is a secreted glycoprotein that is transcriptionally regulated by cholesterol status. It modulates levels of circulating low density lipoprotein cholesterol (LDLC) by negatively regulating low density lipoprotein receptor (LDLR) level...
Autores principales: | Mayne, Janice, Dewpura, Thilina, Raymond, Angela, Cousins, Marion, Chaplin, Anna, Lahey, Karen A, LaHaye, Stephen A, Mbikay, Majambu, Ooi, Teik Chye, Chrétien, Michel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432057/ https://www.ncbi.nlm.nih.gov/pubmed/18547436 http://dx.doi.org/10.1186/1476-511X-7-22 |
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