Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report

INTRODUCTION: A large part of research into drug addiction focuses on mesolimbic dopamine circuitry; however, both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate and dopamine D2 receptors can play a role in maintaining the established addiction. CASE PRESENTATION: We report...

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Detalles Bibliográficos
Autores principales: Arbaizar, Beatriz, Gómez-Acebo, Inés, Llorca, Javier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432067/
https://www.ncbi.nlm.nih.gov/pubmed/18547425
http://dx.doi.org/10.1186/1752-1947-2-198
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author Arbaizar, Beatriz
Gómez-Acebo, Inés
Llorca, Javier
author_facet Arbaizar, Beatriz
Gómez-Acebo, Inés
Llorca, Javier
author_sort Arbaizar, Beatriz
collection PubMed
description INTRODUCTION: A large part of research into drug addiction focuses on mesolimbic dopamine circuitry; however, both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate and dopamine D2 receptors can play a role in maintaining the established addiction. CASE PRESENTATION: We report the case of a 34-year-old man who compulsively smoked 80 to 100 cigarettes each day. After receiving treatment with topiramate and aripiprazole, his tobacco consumption was dramatically reduced. CONCLUSION: Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate blocking agents and a dopamine D2 receptor partial agonist may be novel instruments for nicotine abuse disorders.
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spelling pubmed-24320672008-06-20 Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report Arbaizar, Beatriz Gómez-Acebo, Inés Llorca, Javier J Med Case Reports Case Report INTRODUCTION: A large part of research into drug addiction focuses on mesolimbic dopamine circuitry; however, both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate and dopamine D2 receptors can play a role in maintaining the established addiction. CASE PRESENTATION: We report the case of a 34-year-old man who compulsively smoked 80 to 100 cigarettes each day. After receiving treatment with topiramate and aripiprazole, his tobacco consumption was dramatically reduced. CONCLUSION: Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and/or kainate blocking agents and a dopamine D2 receptor partial agonist may be novel instruments for nicotine abuse disorders. BioMed Central 2008-06-11 /pmc/articles/PMC2432067/ /pubmed/18547425 http://dx.doi.org/10.1186/1752-1947-2-198 Text en Copyright © 2008 Arbaizar et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Arbaizar, Beatriz
Gómez-Acebo, Inés
Llorca, Javier
Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
title Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
title_full Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
title_fullStr Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
title_full_unstemmed Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
title_short Decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
title_sort decrease in tobacco consumption after treatment with topiramate and aripiprazole: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432067/
https://www.ncbi.nlm.nih.gov/pubmed/18547425
http://dx.doi.org/10.1186/1752-1947-2-198
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