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Population Substructure and Control Selection in Genome-Wide Association Studies
Determination of the relevance of both demanding classical epidemiologic criteria for control selection and robust handling of population stratification (PS) represents a major challenge in the design and analysis of genome-wide association studies (GWAS). Empirical data from two GWAS in European Am...
Autores principales: | Yu, Kai, Wang, Zhaoming, Li, Qizhai, Wacholder, Sholom, Hunter, David J., Hoover, Robert N., Chanock, Stephen, Thomas, Gilles |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2432498/ https://www.ncbi.nlm.nih.gov/pubmed/18596976 http://dx.doi.org/10.1371/journal.pone.0002551 |
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