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Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists
Microglia and astrocytes express numerous members of the Toll-like receptor (TLR) family that are pivotal for recognizing conserved microbial motifs expressed by a wide array of pathogens. Despite the critical role for TLRs in pathogen recognition, when dysregulated these pathways can also exacerbat...
Autores principales: | Gurley, Catherine, Nichols, Jessica, Liu, Shuliang, Phulwani, Nirmal K., Esen, Nilufer, Kielian, Tammy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435222/ https://www.ncbi.nlm.nih.gov/pubmed/18584038 http://dx.doi.org/10.1155/2008/453120 |
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