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Increased Responsiveness to Toll-Like Receptor 4 Stimulation in Peripheral Blood Mononuclear Cells from Patients with Recent Onset Rheumatoid Arthritis

Background. Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed to assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, oste...

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Detalles Bibliográficos
Autores principales: Kowalski, M. L., Wolska, A., Grzegorczyk, J., Hilt, J., Jarzebska, M., Drobniewski, M., Synder, M., Kurowski, M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435281/
https://www.ncbi.nlm.nih.gov/pubmed/18584044
http://dx.doi.org/10.1155/2008/132732