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Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach

BACKGROUND: Calmodulin is an important multifunctional molecule that regulates the activities of a large number of proteins in the cell. Calcium binding induces conformational transitions in calmodulin that make it specifically active to particular target proteins. The precise mechanisms underlying...

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Detalles Bibliográficos
Autores principales:	Valeyev, Najl V, Bates, Declan G, Heslop-Harrison, Pat, Postlethwaite, Ian, Kotov, Nikolay V
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435525/ https://www.ncbi.nlm.nih.gov/pubmed/18518982 http://dx.doi.org/10.1186/1752-0509-2-48

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