Cargando…

Multiple congenital oral granular cell tumours in a newborn black female: a case report

INTRODUCTION: Congenital oral granular cell tumour of the newborn is an uncommon benign tumour of uncertain origin. The typical clinical appearance is of a single nodule occurring on the anterior maxillary ridge. In 10% of cases there are multiple lesions. The occurrence of congenital epulis in non-...

Descripción completa

Detalles Bibliográficos
Autores principales: Feller, Liviu, Wood, Neil H, Singh, Avin S, Raubenheimer, Erich J, Meyerov, Robin, Lemmer, Johan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438317/
https://www.ncbi.nlm.nih.gov/pubmed/18577259
http://dx.doi.org/10.1186/1757-1626-1-13
_version_ 1782156505127059456
author Feller, Liviu
Wood, Neil H
Singh, Avin S
Raubenheimer, Erich J
Meyerov, Robin
Lemmer, Johan
author_facet Feller, Liviu
Wood, Neil H
Singh, Avin S
Raubenheimer, Erich J
Meyerov, Robin
Lemmer, Johan
author_sort Feller, Liviu
collection PubMed
description INTRODUCTION: Congenital oral granular cell tumour of the newborn is an uncommon benign tumour of uncertain origin. The typical clinical appearance is of a single nodule occurring on the anterior maxillary ridge. In 10% of cases there are multiple lesions. The occurrence of congenital epulis in non-Caucasians is rare. CASE PRESENTATION: Two firm pedunculated nodular lesions were noticed in the mouth of a 3-day-old black female: one on the anterior maxillary ridge and the other further posteriorly in the midline of the palate. Both lesions were excised when the baby was nine days old. Microscopic examination of the lesions showed densely packed round to oval cells with abundant granular eosinophilic cytoplasm and uniform nuclei. The diagnosis was congenital granular cell tumour. CONCLUSION: Congenital oral granular cell tumour occurs almost exclusively in Caucasian newborns but also rarely in black infants. The parents should be assured of the benign nature and the simple treatment of the condition.
format Text
id pubmed-2438317
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-24383172008-06-25 Multiple congenital oral granular cell tumours in a newborn black female: a case report Feller, Liviu Wood, Neil H Singh, Avin S Raubenheimer, Erich J Meyerov, Robin Lemmer, Johan Cases J Case Report INTRODUCTION: Congenital oral granular cell tumour of the newborn is an uncommon benign tumour of uncertain origin. The typical clinical appearance is of a single nodule occurring on the anterior maxillary ridge. In 10% of cases there are multiple lesions. The occurrence of congenital epulis in non-Caucasians is rare. CASE PRESENTATION: Two firm pedunculated nodular lesions were noticed in the mouth of a 3-day-old black female: one on the anterior maxillary ridge and the other further posteriorly in the midline of the palate. Both lesions were excised when the baby was nine days old. Microscopic examination of the lesions showed densely packed round to oval cells with abundant granular eosinophilic cytoplasm and uniform nuclei. The diagnosis was congenital granular cell tumour. CONCLUSION: Congenital oral granular cell tumour occurs almost exclusively in Caucasian newborns but also rarely in black infants. The parents should be assured of the benign nature and the simple treatment of the condition. BioMed Central 2008-05-30 /pmc/articles/PMC2438317/ /pubmed/18577259 http://dx.doi.org/10.1186/1757-1626-1-13 Text en Copyright © 2008 Feller et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Feller, Liviu
Wood, Neil H
Singh, Avin S
Raubenheimer, Erich J
Meyerov, Robin
Lemmer, Johan
Multiple congenital oral granular cell tumours in a newborn black female: a case report
title Multiple congenital oral granular cell tumours in a newborn black female: a case report
title_full Multiple congenital oral granular cell tumours in a newborn black female: a case report
title_fullStr Multiple congenital oral granular cell tumours in a newborn black female: a case report
title_full_unstemmed Multiple congenital oral granular cell tumours in a newborn black female: a case report
title_short Multiple congenital oral granular cell tumours in a newborn black female: a case report
title_sort multiple congenital oral granular cell tumours in a newborn black female: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438317/
https://www.ncbi.nlm.nih.gov/pubmed/18577259
http://dx.doi.org/10.1186/1757-1626-1-13
work_keys_str_mv AT fellerliviu multiplecongenitaloralgranularcelltumoursinanewbornblackfemaleacasereport
AT woodneilh multiplecongenitaloralgranularcelltumoursinanewbornblackfemaleacasereport
AT singhavins multiplecongenitaloralgranularcelltumoursinanewbornblackfemaleacasereport
AT raubenheimererichj multiplecongenitaloralgranularcelltumoursinanewbornblackfemaleacasereport
AT meyerovrobin multiplecongenitaloralgranularcelltumoursinanewbornblackfemaleacasereport
AT lemmerjohan multiplecongenitaloralgranularcelltumoursinanewbornblackfemaleacasereport