The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population

BACKGROUND: Mutations in the mismatch repair genes hMLH1 and hMSH2 predispose to hereditary non-polyposis colorectal cancer (HNPCC). Genetic screening of more than 350 Danish patients with colorectal cancer (CRC) has led to the identification of several new genetic variants (e.g. missense, silent an...

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Detalles Bibliográficos
Autores principales: Christensen, Lise Lotte, Madsen, Bo E, Wikman, Friedrik P, Wiuf, Carsten, Koed, Karen, Tjønneland, Anne, Olsen, Anja, Syvänen, Ann-Christine, Andersen, Claus L, Ørntoft, Torben F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438340/
https://www.ncbi.nlm.nih.gov/pubmed/18547406
http://dx.doi.org/10.1186/1471-2350-9-52

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