Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE(2 )production in human chondrocytes in vitro

Several recent studies have documented that supplementation with pomegranate fruit extract inhibits inflammatory symptoms in vivo. However, the molecular basis of the observed effects has not been fully revealed. Although previous studies have documented the inhibition of nitric oxide and cyclooxyge...

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Detalles Bibliográficos
Autores principales: Shukla, Meenakshi, Gupta, Kalpana, Rasheed, Zafar, Khan, Khursheed A, Haqqi, Tariq M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438359/
https://www.ncbi.nlm.nih.gov/pubmed/18554383
http://dx.doi.org/10.1186/1476-9255-5-9

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