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Loss of thalamic serotonin transporters in early drug-naïve Parkinson’s disease patients is associated with tremor: an [(123)I]β-CIT SPECT study

In vitro studies revealed serotonin transporter (5-HTT) decline in Parkinson’s disease (PD). Yet, few studies investigated thalamic 5-HTT in vivo and its effect on PD heterogeneity. We analyzed thalamic [(123)I]β-CIT binding (mainly reflecting 5-HTT binding) in 32 drug-naïve PD patients and 13 contr...

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Detalles Bibliográficos
Autores principales: Caretti, V., Stoffers, D., Winogrodzka, A., Isaias, I.-U., Costantino, G., Pezzoli, G., Ferrarese, C., Antonini, A., Wolters, E.-Ch., Booij, J.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440940/
https://www.ncbi.nlm.nih.gov/pubmed/18335163
http://dx.doi.org/10.1007/s00702-007-0015-2