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Computational approaches for modeling human intestinal absorption and permeability

Human intestinal absorption (HIA) is an important roadblock in the formulation of new drug substances. Computational models are needed for the rapid estimation of this property. The measurements are determined via in vivo experiments or in vitro permeability studies. We present several computational...

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Detalles Bibliográficos
Autores principales: Subramanian, Govindan, Kitchen, Douglas B.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441499/
https://www.ncbi.nlm.nih.gov/pubmed/16583199
http://dx.doi.org/10.1007/s00894-005-0065-z