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Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe
We developed a technique for electrochemical detection of salivary mRNA employing a hairpin probe (HP). Steric hindrance (SH) suppresses unspecific signal and generates a signal-on amplification process for target detection. The stem-loop configuration brings the reporter end of the probe into close...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441804/ https://www.ncbi.nlm.nih.gov/pubmed/18487624 http://dx.doi.org/10.1093/nar/gkn299 |