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A single amino acid change in histone H4 enhances UV survival and DNA repair in yeast

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Single amino acid changes at specific DNA contacts of histones H3 and H4 generate SWI/SNF-independent (Sin) mutants in yeast. We have analyzed the effect of the Sin mutation at R45 of histone H4 on cell survival following UV irradiation, nucleotide excision repair (NER) and chromatin structure. We f...

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Detalles Bibliográficos
Autores principales:	Nag, Ronita, Gong, Feng, Fahy, Deirdre, Smerdon, Michael J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441814/ https://www.ncbi.nlm.nih.gov/pubmed/18508805 http://dx.doi.org/10.1093/nar/gkn311

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