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SCUMBLE: a method for systematic and accurate detection of codon usage bias by maximum likelihood estimation
The genetic code is degenerate—most amino acids can be encoded by from two to as many as six different codons. The synonymous codons are not used with equal frequency: not only are some codons favored over others, but also their usage can vary significantly from species to species and between differ...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441815/ https://www.ncbi.nlm.nih.gov/pubmed/18495752 http://dx.doi.org/10.1093/nar/gkn288 |