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Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells
The primary targets for SARS-CoV infection are the epithelial cells in the respiratory and intestinal tract. The angiotensin-converting enzyme 2 (ACE-2) has been identified as a functional receptor for SARS-CoV. ACE-2 has been shown to be expressed at the apical domain of polarized Calu-3 cells. In...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc. Published by Elsevier Inc.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441846/ https://www.ncbi.nlm.nih.gov/pubmed/18406349 http://dx.doi.org/10.1016/j.bbrc.2008.04.006 |