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Histone Deacetylases Control Neurogenesis in Embryonic Brain by Inhibition of BMP2/4 Signaling

BACKGROUND: Histone-modifying enzymes are essential for a wide variety of cellular processes dependent upon changes in gene expression. Histone deacetylases (HDACs) lead to the compaction of chromatin and subsequent silencing of gene transcription, and they have recently been implicated in a diversi...

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Detalles Bibliográficos
Autores principales: Shakèd, Maya, Weissmüller, Kathrin, Svoboda, Hanno, Hortschansky, Peter, Nishino, Norikazu, Wölfl, Stefan, Tucker, Kerry L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441862/
https://www.ncbi.nlm.nih.gov/pubmed/18628975
http://dx.doi.org/10.1371/journal.pone.0002668