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Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers

Variation in penetrance estimates for BRCA1/2 carriers suggests that other environmental and genetic factors may modify cancer risk in carriers. The GSTM1, T1 and P1 isoenzymes are involved in metabolism of environmental carcinogens. The GSTM1 and GSTT1 gene is absent in a substantial proportion of...

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Detalles Bibliográficos
Autores principales:	Kadouri, L, Kote-Jarai, Z, Hubert, A, Baras, M, Abeliovich, D, Hamburger, T, Peretz, T, Eeles, R A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441947/ https://www.ncbi.nlm.nih.gov/pubmed/18542066 http://dx.doi.org/10.1038/sj.bjc.6604394

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