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Tumour–stroma interactions in colorectal cancer: converging on β-catenin activation and cancer stemness
Sporadic cases of colorectal cancer are primarily initiated by gene mutations in members of the canonical Wnt pathway, ultimately resulting in β-catenin stabilisation. Nevertheless, cells displaying nuclear β-catenin accumulation are nonrandomly distributed throughout the tumour mass and preferentia...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441948/ https://www.ncbi.nlm.nih.gov/pubmed/18506144 http://dx.doi.org/10.1038/sj.bjc.6604401 |