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Oxaliplatin-DNA adduct formation in white blood cells of cancer patients

In this study, we investigated the kinetics of oxaliplatin-DNA adduct formation in white blood cells of cancer patients in relation to efficacy as well as oxaliplatin-associated neurotoxicity. Thirty-seven patients with various solid tumours received 130 mg m(−2) oxaliplatin as a 2-h infusion. Oxali...

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Detalles Bibliográficos
Autores principales:	Pieck, A C, Drescher, A, Wiesmann, K G, Messerschmidt, J, Weber, G, Strumberg, D, Hilger, R A, Scheulen, M E, Jaehde, U
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441951/ https://www.ncbi.nlm.nih.gov/pubmed/18506148 http://dx.doi.org/10.1038/sj.bjc.6604387

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