Cargando…
Interactions between APP secretases and inflammatory mediators
There is now a large body of evidence linking inflammation to Alzheimer's disease (AD). This association manifests itself neuropathologically in the presence of activated microglia and astrocytes around neuritic plaques and increased levels of inflammatory mediators in the brains of AD patients...
Autores principales: | Sastre, Magdalena, Walter, Jochen, Gentleman, Steve M |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442055/ https://www.ncbi.nlm.nih.gov/pubmed/18564425 http://dx.doi.org/10.1186/1742-2094-5-25 |
Ejemplares similares
-
Presenilins and γ-Secretase in Membrane Proteostasis
por: Oikawa, Naoto, et al.
Publicado: (2019) -
Enzyme–substrate interface targeting by imidazole‐based γ‐secretase modulators activates γ‐secretase and stabilizes its interaction with APP
por: Petit, Dieter, et al.
Publicado: (2022) -
NSAIDs: How they Work and their Prospects as Therapeutics in Alzheimer's Disease
por: Sastre, Magdalena, et al.
Publicado: (2010) -
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not
por: Lessard, Christian B., et al.
Publicado: (2020) -
High Resolution Imaging Study of Interactions between the 37 kDa/67 kDa Laminin Receptor and APP, Beta-Secretase and Gamma-Secretase in Alzheimer's Disease
por: Jovanovic, Katarina, et al.
Publicado: (2014)