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Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway

Endocytosis of the nicotinic acetylcholine receptor (AChR) is a proposed major mechanism of neuromodulation at neuromuscular junctions and in the pathology of synapses in the central nervous system. We show that binding of the competitive antagonist α-bungarotoxin (αBTX) or antibody-mediated cross-l...

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Detalles Bibliográficos
Autores principales: Kumari, Sudha, Borroni, Virginia, Chaudhry, Ashutosh, Chanda, Baron, Massol, Ramiro, Mayor, Satyajit, Barrantes, Francisco J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442195/
https://www.ncbi.nlm.nih.gov/pubmed/18591431
http://dx.doi.org/10.1083/jcb.200709086