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Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins
Misfolded proteins in the endoplasmic reticulum (ER) are identified and degraded by the ER-associated degradation pathway (ERAD), a component of ER quality control. In ERAD, misfolded proteins are removed from the ER by retrotranslocation into the cytosol where they are degraded by the ubiquitin–pro...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442213/ https://www.ncbi.nlm.nih.gov/pubmed/18573918 http://dx.doi.org/10.1083/jcb.200804053 |