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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

Platelet activation and aggregation are essential to limit posttraumatic blood loss at sites of vascular injury but also contributes to arterial thrombosis, leading to myocardial infarction and stroke. Agonist-induced elevation of [Ca(2+)](i) is a central step in platelet activation, but the underly...

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Detalles Bibliográficos
Autores principales: Varga-Szabo, David, Braun, Attila, Kleinschnitz, Christoph, Bender, Markus, Pleines, Irina, Pham, Mirko, Renné, Thomas, Stoll, Guido, Nieswandt, Bernhard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442636/
https://www.ncbi.nlm.nih.gov/pubmed/18559454
http://dx.doi.org/10.1084/jem.20080302