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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
Platelet activation and aggregation are essential to limit posttraumatic blood loss at sites of vascular injury but also contributes to arterial thrombosis, leading to myocardial infarction and stroke. Agonist-induced elevation of [Ca(2+)](i) is a central step in platelet activation, but the underly...
Autores principales: | Varga-Szabo, David, Braun, Attila, Kleinschnitz, Christoph, Bender, Markus, Pleines, Irina, Pham, Mirko, Renné, Thomas, Stoll, Guido, Nieswandt, Bernhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442636/ https://www.ncbi.nlm.nih.gov/pubmed/18559454 http://dx.doi.org/10.1084/jem.20080302 |
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