Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

The ribonucleic acid (RNA) helicases retinoic acid-inducible gene-I (RIG-I) and melanoma differentiation–associated gene 5 (MDA5) recognize distinct viral and synthetic RNAs, leading to the production of interferons. Although 5′-triphosphate single-stranded RNA is a RIG-I ligand, the role of RIG-I a...

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Detalles Bibliográficos
Autores principales: Kato, Hiroki, Takeuchi, Osamu, Mikamo-Satoh, Eriko, Hirai, Reiko, Kawai, Tomoji, Matsushita, Kazufumi, Hiiragi, Akane, Dermody, Terence S., Fujita, Takashi, Akira, Shizuo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442638/
https://www.ncbi.nlm.nih.gov/pubmed/18591409
http://dx.doi.org/10.1084/jem.20080091

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