Both Functional LTβ Receptor and TNF Receptor 2 Are Required for the Development of Experimental Cerebral Malaria

BACKGROUND: TNF-related lymphotoxin α (LTα) is essential for the development of Plasmodium berghei ANKA (PbA)-induced experimental cerebral malaria (ECM). The pathway involved has been attributed to TNFR2. Here we show a second arm of LTα-signaling essential for ECM development through LTβ-R, recept...

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Detalles Bibliográficos
Autores principales: Togbe, Dieudonnée, Loureiro de Sousa, Paulo, Fauconnier, Mathilde, Boissay, Victorine, Fick, Lizette, Scheu, Stefanie, Pfeffer, Klaus, Menard, Robert, Grau, Georges E., Doan, Bich-Thuy, Beloeil, Jean Claude, Renia, Laurent, Hansen, Anna M., Ball, Helen J., Hunt, Nicholas H., Ryffel, Bernhard, Quesniaux, Valerie F. J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442868/
https://www.ncbi.nlm.nih.gov/pubmed/18612394
http://dx.doi.org/10.1371/journal.pone.0002608

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