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Modulation of NKT Cell Development by B7-CD28 Interaction: An Expanding Horizon for Costimulation
It has been demonstrated that the development of NKT cells requires CD1d. The contribution of costimulatory molecules in this process has not been studied. Here we show that in mice with targeted mutations of B7-1/2 and CD28, the TCRβ(+)α-Galcer/CD1d (+) (iVα14 NKT) subset is significantly reduced i...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442875/ https://www.ncbi.nlm.nih.gov/pubmed/18628995 http://dx.doi.org/10.1371/journal.pone.0002703 |