Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?

The only curative treatment for proximal bile duct cancer with involvement of both main hepatic ducts is liver transplantation. Most patients do not fulfill the requirements for liver transplantation. Our treatment strategy in appropriate cases is palliative tumor resection and reconstruction of the...

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Detalles Bibliográficos
Autores principales: Wilker, Dietmar K., Izbicki, Jakob R., Rohloff, Ralf, Knoefel, Wolfram-T., Mandelkow, Hans, Schweiberer, Leonhard
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442966/
https://www.ncbi.nlm.nih.gov/pubmed/1382557
http://dx.doi.org/10.1155/1992/91670
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author Wilker, Dietmar K.
Izbicki, Jakob R.
Rohloff, Ralf
Knoefel, Wolfram-T.
Mandelkow, Hans
Schweiberer, Leonhard
author_facet Wilker, Dietmar K.
Izbicki, Jakob R.
Rohloff, Ralf
Knoefel, Wolfram-T.
Mandelkow, Hans
Schweiberer, Leonhard
author_sort Wilker, Dietmar K.
collection PubMed
description The only curative treatment for proximal bile duct cancer with involvement of both main hepatic ducts is liver transplantation. Most patients do not fulfill the requirements for liver transplantation. Our treatment strategy in appropriate cases is palliative tumor resection and reconstruction of the biliary passage by sutureless bilioenteric anastomosis. We have treated 12 patients, 5 in combination with intraluminal and percutaneous radiotherapy. Our results indicate that this strategy leads to effective palliation in some cases provided that only microscopic residual tumor is left in-situ. Our survival times compare favourably with survival after liver transplantation.
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spelling pubmed-24429662008-07-08 Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile? Wilker, Dietmar K. Izbicki, Jakob R. Rohloff, Ralf Knoefel, Wolfram-T. Mandelkow, Hans Schweiberer, Leonhard HPB Surg Research Article The only curative treatment for proximal bile duct cancer with involvement of both main hepatic ducts is liver transplantation. Most patients do not fulfill the requirements for liver transplantation. Our treatment strategy in appropriate cases is palliative tumor resection and reconstruction of the biliary passage by sutureless bilioenteric anastomosis. We have treated 12 patients, 5 in combination with intraluminal and percutaneous radiotherapy. Our results indicate that this strategy leads to effective palliation in some cases provided that only microscopic residual tumor is left in-situ. Our survival times compare favourably with survival after liver transplantation. Hindawi Publishing Corporation 1992 /pmc/articles/PMC2442966/ /pubmed/1382557 http://dx.doi.org/10.1155/1992/91670 Text en Copyright © 1992 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wilker, Dietmar K.
Izbicki, Jakob R.
Rohloff, Ralf
Knoefel, Wolfram-T.
Mandelkow, Hans
Schweiberer, Leonhard
Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?
title Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?
title_full Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?
title_fullStr Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?
title_full_unstemmed Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?
title_short Is Aggressive Surgical Palliation of Proximal Bile Duct Cancer With Involvement of Both Main Hepatic Ducts Worthwhile?
title_sort is aggressive surgical palliation of proximal bile duct cancer with involvement of both main hepatic ducts worthwhile?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442966/
https://www.ncbi.nlm.nih.gov/pubmed/1382557
http://dx.doi.org/10.1155/1992/91670
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