Cargando…
The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis
The pancreatic cancer continues to represent an important problem, as a cancer with extremely poor prognosis. To date more than 16 chemicals have been shown to induce pancreatic tumors, in animal models. The tumors developed in rats are essentially of acinar type and those in hamsters mostly of duct...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1993
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443050/ https://www.ncbi.nlm.nih.gov/pubmed/8489964 http://dx.doi.org/10.1155/1993/70454 |
_version_ | 1782156778159472640 |
---|---|
author | Christopoulou, A. Blanc, F. Joyeux, H. |
author_facet | Christopoulou, A. Blanc, F. Joyeux, H. |
author_sort | Christopoulou, A. |
collection | PubMed |
description | The pancreatic cancer continues to represent an important problem, as a cancer with extremely poor prognosis. To date more than 16 chemicals have been shown to induce pancreatic tumors, in animal models. The tumors developed in rats are essentially of acinar type and those in hamsters mostly of ductal type. Many studies proved the direct or indirect role of hormonal and dietary factors in pancreatic cancer. The development of alternative treatments according to biological and biochemical steps of carcinogenesis is available as adjuvant treatment. We present herein an overview of current experimental and clinical results in order to understand the evolution, histogenesis and biological behaviour of pancreatic cancer. |
format | Text |
id | pubmed-2443050 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1993 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-24430502008-07-08 The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis Christopoulou, A. Blanc, F. Joyeux, H. HPB Surg Research Article The pancreatic cancer continues to represent an important problem, as a cancer with extremely poor prognosis. To date more than 16 chemicals have been shown to induce pancreatic tumors, in animal models. The tumors developed in rats are essentially of acinar type and those in hamsters mostly of ductal type. Many studies proved the direct or indirect role of hormonal and dietary factors in pancreatic cancer. The development of alternative treatments according to biological and biochemical steps of carcinogenesis is available as adjuvant treatment. We present herein an overview of current experimental and clinical results in order to understand the evolution, histogenesis and biological behaviour of pancreatic cancer. Hindawi Publishing Corporation 1993 /pmc/articles/PMC2443050/ /pubmed/8489964 http://dx.doi.org/10.1155/1993/70454 Text en Copyright © 1993 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Christopoulou, A. Blanc, F. Joyeux, H. The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis |
title | The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis |
title_full | The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis |
title_fullStr | The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis |
title_full_unstemmed | The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis |
title_short | The Role of Hormonal and Dietary Factors in Pancreatic Carcinogenesis |
title_sort | role of hormonal and dietary factors in pancreatic carcinogenesis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443050/ https://www.ncbi.nlm.nih.gov/pubmed/8489964 http://dx.doi.org/10.1155/1993/70454 |
work_keys_str_mv | AT christopouloua theroleofhormonalanddietaryfactorsinpancreaticcarcinogenesis AT blancf theroleofhormonalanddietaryfactorsinpancreaticcarcinogenesis AT joyeuxh theroleofhormonalanddietaryfactorsinpancreaticcarcinogenesis AT christopouloua roleofhormonalanddietaryfactorsinpancreaticcarcinogenesis AT blancf roleofhormonalanddietaryfactorsinpancreaticcarcinogenesis AT joyeuxh roleofhormonalanddietaryfactorsinpancreaticcarcinogenesis |