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Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution
BACKGROUND: Vaccination of macaques with live attenuated simian immunodeficiency virus (SIV) provides significant protection against the wild-type virus. The use of a live attenuated human immunodeficiency virus (HIV) as AIDS vaccine in humans is however considered unsafe because of the risk that th...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443169/ https://www.ncbi.nlm.nih.gov/pubmed/18533993 http://dx.doi.org/10.1186/1742-4690-5-44 |