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A Histone Methyltransferase Modulates Antigenic Variation in African Trypanosomes
To evade the host immune system, several pathogens periodically change their cell-surface epitopes. In the African trypanosomes, antigenic variation is achieved by tightly regulating the expression of a multigene family encoding a large repertoire of variant surface glycoproteins (VSGs). Immune evas...
Autores principales: | Figueiredo, Luisa M, Janzen, Christian J, Cross, George A.M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443197/ https://www.ncbi.nlm.nih.gov/pubmed/18597556 http://dx.doi.org/10.1371/journal.pbio.0060161 |
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