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Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer

Aromatic amines, N-nitroso compounds and heterocyclic amines are suspected human pancreatic carcinogens. Cytochrome P450 (CYP) 1A2, N-acetyltransferase (NAT) 1, NAT2 and sulfotransferase (SULT) are enzymes involved in the metabolism of these carcinogens. To test the hypothesis that genetic variation...

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Detalles Bibliográficos
Autores principales:	Suzuki, Hideo, Morris, Jeffrey S., Li, Yanan, Doll, Mark A., Hein, David W., Liu, Jun, Jiao, Li, Hassan, Manal M., Day, Rena S., Bondy, Melissa L., Abbruzzese, James L., Li, Donghui
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Epidemiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443278/ https://www.ncbi.nlm.nih.gov/pubmed/18499698 http://dx.doi.org/10.1093/carcin/bgn085

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