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E1 Ubiquitin-Activating Enzyme UBA-1 Plays Multiple Roles throughout C. elegans Development

Poly-ubiquitination of target proteins typically marks them for destruction via the proteasome and provides an essential mechanism for the dynamic control of protein levels. The E1 ubiquitin-activating enzyme lies at the apex of the ubiquitination cascade, and its activity is necessary for all subse...

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Detalles Bibliográficos
Autores principales:	Kulkarni, Madhura, Smith, Harold E.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443343/ https://www.ncbi.nlm.nih.gov/pubmed/18636104 http://dx.doi.org/10.1371/journal.pgen.1000131

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